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          Zanzibar Highlights !!!                
Click here to view presentations and notes of EA IeDEA Executive Committee meeting held last May 4-5, 2010 in Zanzibar or click the Presentations link above

The AIDS pandemic is one of the greatest public health challenges of our lifetime. According to UNAIDS and WHO statistics, in 2007, 33.2 million people globally were estimated to be living with HIV. Given the size and geographical spread of HIV/AIDS, a well coordinated international effort is required in order to study variations in the disease between populations and to identify optimal treatment and prevention strategies across a spectrum of contexts. In developing countries, successful initiatives must combine an extensive knowledge of retroviral biology, human immunology, and geographically defined microbial milieus with a keen understanding of local cultures, economies and health care infrastructures. A myriad of barriers to the optimal delivery of services to affected populations must also be addressed, while remaining vigilant to the ethical dimensions of implementing treatment and prevention programs in resource-limited settings. Thus, the very nature of the HIV/AIDS epidemic requires that knowledge and information be combined and translated across multiple ethnic, cultural, economic and religious groups. This necessitates integrated communication and efficient, bi-directional sharing of data among collaborating provider and researcher networks in East Africa. Indeed, reliable data and information sharing has repeatedly been cited as the single most cost effective and achievable strategy for sustainable improvement in health care in developing countries, particularly in support of HIV care. East African IeDEA is utilizing data collected in an array of HIV clinical venues to address the following issues:
  • Cost-effectiveness of HIV care, treatment, and prevention strategies
  • Appropriate guidelines for initiation of first-line therapy for treatment of   HIV/AIDS
  • Genetic variability of HIV
  • Issues related to first-line therapy failure
  • Adherence to HIV treatment
  • Contextual issues and resource limitations of HIV care delivery in resource-limited settings
  • Impact of tuberculosis infection on HIV/AIDS care and treatment in developing world
  • Prevention of mother-to-child transmission of HIV
  • Issues in the treatment and management of HIV-infected children